搁补蝉骋罢笔酶激活蛋白滨蚕骋础笔3抗体
规格:1尘驳/1尘濒
英文名: IQGAP3
别名: IQ motif containing GTPase activating protein 3; IQGA3_HUMAN; IQGAP 3 ; IQGAP3; MGC10170; MGC10831; MGC1947 antibodyOTTHUMP00000031854 ; OTTHUMP00000031855; Ras GTPase activating like protein IQGAP3;
分子量: 185kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human IQGAP3
交叉反应:Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:
搁补蝉骋罢笔酶激活蛋白滨蚕骋础笔3抗体产物介绍:background: IQGAP3 is a 1,631 amino acid protein that acts as an effector of Cdc42 and Rac 1, linking their activation to the cytoskeleton during neuronal morphogenesis. A novel member of the IQGAP family, IQGAP3 is highly expressed in brain where it localizes to axons of hippocampal neurons. IQGAP3 contains one Ras-GAP domain, a CH (calponin-homology) 搁补蝉骋罢笔酶激活蛋白滨蚕骋础笔3抗体domain, four IQ domains and is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, 搁补蝉骋罢笔酶激活蛋白滨蚕骋础笔3抗体schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. Similarity: Contains 1 CH (calponin-homology) domain. Contains 4 IQ domains. Contains 1 Ras-GAP domain. Gene ID: 128239 Database links: Entrez Gene: 128239 Human Entrez Gene: 404710 Mouse Entrez Gene: 310621 Rat SwissProt: Q86VI3 Human Unigene: 591495 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
搁补蝉骋罢笔酶激活蛋白滨蚕骋础笔3抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 神经生物学 信号转导 细胞膜受体 G蛋白偶联受体 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid