有脊椎动物脑发育相关蛋白贰尘虫1抗体
规格:1尘驳/1尘濒
英文名: Emx1
别名: Empty spiracles homeobox 1; Empty spiracles homolog 1; empty spiracles homolog 1 Drosophila antibodyEmpty spiracles like protein 1; Empty spiracles-like protein 1; EMX1 ; EMX1_HUMAN ; Homeobox protein
分子量: 29kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Emx1
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞核
有脊椎动物脑发育相关蛋白贰尘虫1抗体产物介绍:background: Emx1 and Emx2 are human homologs to the Drosophila developmental genes empty spiracles expressed in anterior body regions during early Drosophila embryogenesis. Emx1 and Emx2 are homeobox proteins expressed in the developing vertebrate brain. Emx2 is expressed in the dorsal telencephalon and small diencephalic regions, while Emx1 expression is exclusively confined to pyramidal neurons of the dorsal telencephalon. In the embryonic brain, Emx1 is expressed in both proliferating and differentiating有脊椎动物脑发育相关蛋白贰尘虫1抗体 neurons while Emx2 is expressed only in proliferating neurons. OTX1 and OTX2 are human homologs of the Drosophila developmental genes orthodenticle. In development, the sequence of expression begins with OTX2 at day 10 post coitum followed by OTX1, Emx2 and finally Emx1. The genes encoding human Emx1 and Emx2 map to chromosomes 2p14-p13 and 10q26.1, respectively. Function: 有脊椎动物脑发育相关蛋白贰尘虫1抗体Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system. Subcellular Location: Nucleus. Tissue Specificity: Cerebral cortex. Similarity: Belongs to the EMX homeobox family. Contains 1 homeobox DNA-binding domain. Database links: UniProtKB/Swiss-Prot: Q04741.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
有脊椎动物脑发育相关蛋白贰尘虫1抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 发育生物学 神经生物学 信号转导 干细胞 转录调节因子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid