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Ó¢ÎÄÃû£º Cux2
±ðÃû£º CDP2; Cut like homeobox 2; Cut-like 2; CUTL2; CUX2; Homeobox protein cut-like 2; Homeobox protein cux 2; Homeobox protein Cux-2; KIAA0293; CUX2_HUMAN.
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´¿»¯·½·¨£ºaffinity purified by Protein A
**KLH conjugated synthetic peptide derived from human Cux2 (10
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ת¼ͬԴµ°°×Öʰ䱫³Ý2¿¹Ìå²úÎï½éÉÜ£ºbackground: Cux2 is a marker for cortical subpopulations. Cux2 is an orthologue of the Drosophila cut gene, which encodes a homeodomain protein involved in neuronal specification. During cortical development Cux2 identifies two subpopulations with different spatial origins, migratory behaviours and phenotypic characteristics: (i) a population of interneurons, which invades the palliumת¼ͬԴµ°°×Öʰ䱫³Ý2¿¹Ìå from the subpallium; and (ii) a neuronal population produced in the pallium around embryonic day 11.5, which divides in the SVZ and accumulates in the intermediate zone (IZ). Subsequently, Cux2 is a marker of upper cortical layers. Function: May be a transcription factor involved in neural specification. Binds to DNA in a sequence-specific manner Subcellular Location: Nuclear Similarity: Belongs to the CUT homeobox family. Contains 3 CUT DNA-binding domains. Contains 1 homeobox DNA-binding domain. Gene ID: 23316 Database links: Entrez Gene:ת¼ͬԴµ°°×Öʰ䱫³Ý2¿¹Ìå 23316 Human Entrez Gene: 13048 Mouse Entrez Gene: 288665 Rat Omim: 610648 Human SwissProt: O14529 Human SwissProt: P70298 Mouse Unigene: 124953 Human Unigene: 156172 Mouse Unigene: 332661 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ת¼ͬԴµ°°×Öʰ䱫³Ý2¿¹Ìå²úÎïÓ¦ÓãºELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 £¨Ê¯À¯ÇÐÆ¬Ðè×ö¿¹ÔÐÞ¸´£© not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
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´¢´æÌõ¼þ£º Store at -20 ¡ãC for one year. Avoid repeated freeze/thaw cycles.
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Íâ¹Û£º Lyophilized or Liquid