顿鲍尝尝础搁顿蛋白抗体
规格：1尘驳/1尘濒
英文名： DULLARD
别名： Dullard homolog; HSA 011916; NET 56 antibodySerine threonine protein phosphatase dullard; CNEP1_HUMAN.
分子量： 28kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DULLARD
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse,
细胞定位：细胞核 细胞浆 细胞膜
顿鲍尝尝础搁顿蛋白抗体产物介绍：background: In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. Dullard, also known as NET56, is a 244 amino acid single-pass membrane protein that localizes to both the nucleus and the endoplasmic reticulum and contains one FCP1 homology domain. Functioning as a serine/threonine顿鲍尝尝础搁顿蛋白抗体 phosphatase, Dullard catalyses the dephosphorylation of target proteins and is thought to be required for proper nuclear membrane morphology. Human Dullard shares 92% sequence identity with its zebrafish counterpart, suggesting a conserved role between species. Function: DULLARD is a serine/threonine phosphatase which may be required for proper nuclear membrane morphology. It is involved in LPIN1 dephosphorylation and may antagonize BMP signaling. Subunit: Interacts with CNEP1R1; the complex dephosphorylates LPIN1 and LPIN2. 顿鲍尝尝础搁顿蛋白抗体Subcellular Location: Endoplasmic reticulum membrane; Single-pass membrane protein. Nuclear membrane; Single-pass membrane protein. Tissue Specificity: Muscle specific with lower expression in other metabolic tissues. Similarity: Belongs to the dullard family. Contains 1 FCP1 homology domain. Database links: UniProtKB/Swiss-Prot: O95476.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
顿鲍尝尝础搁顿蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 信号转导 激酶和磷酸酶 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid