骋蛋白偶联受体10抗体
规格:1尘驳/1尘濒
英文名: GPR10
别名: G protein coupled receptor 10; G-protein coupled receptor 10; GPR 10; GPR10; GCPR 10; GR 3; GR3; hGR 3; hGR3; MGC126539; MGC126541; PRLH RECEPTOR; PRLHR; PRLHR_HUMAN; Prolactin releasing hormone recep
分子量: 41kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human G protei
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Sheep, Monkey, y
细胞定位:细胞膜
骋蛋白偶联受体10抗体产物介绍:background: G protein-coupled receptors (GPRs or GPCRs), also known as seven transmembrane receptors, heptahelical receptors, or 7TM receptors, are members of the largest protein family and play a role in many different stimulus-response pathways. G-protein coupled receptors mediate extracellular signals into intracellular signals (G-protein activation). They respond to a great variety of signaling molecules, including hormones, neurotransmitters and other proteins and peptides. GPR proteins are integral seven-pass membrane proteins with some conserved amino acid regions. G-protein coupled receptor 10 (GPR10) acts as a receptor for prolactin-releasing peptide骋蛋白偶联受体10抗体 (PrRP). GPR10 plays a role in the regulation of food intake, pain-signal processing and lactation. Primarily expressed in pituitary gland, it is repressed by bromocriptine. GPR10 interacts with various other proteins, including GRIP1, GRIP2 and PICK1. Function: Receptor for prolactin-releasing peptide (PrRP). Implicated in lactation, regulation of food intake and pain-signal processing. Subunit: Interacts through its C-terminal region with the PDZ domain-containing proteins GRIP1, GRIP2 and PICK1. Interacts with PDZ domains 4 and 5 of GRIP1 and with the PDZ domain of PICK1. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Only detected in the pituitary gland and in all cell types of pituitary 骋蛋白偶联受体10抗体adenomas. Similarity: Belongs to the G-protein coupled receptor 1 family. Gene ID: 2834 Database links: Entrez Gene: 510397 Cow Entrez Gene: 486911 Dog Entrez Gene: 2834 Human Entrez Gene: 100412185 Marmoset (common) Entrez Gene: 226278 Mouse Entrez Gene: 100523144 Pig Entrez Gene: 246075 Rat Omim: 600895 Human SwissProt: Q4EW11 Cow SwissProt: P49683 Human SwissProt: Q6VMN6 Mouse SwissProt: Q64121 Rat Unigene: 248119 Human Unigene: 377241 Mouse Unigene: 138127 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
骋蛋白偶联受体10抗体产物应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:神经生物学 信号转导 G蛋白偶联受体 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid