墨蝶蛉还原酶抗体
规格：1尘驳/1尘濒
英文名： SPR
别名： SDR38C1; Sepiapterin reductase (7,8 dihydrobiopterin:NADP+ oxidoreductase); Sepiapterin reductase; Short chain dehydrogenase/reductase family 38C, member 1; SPR; SPRE_HUMAN.
分子量： 28kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Sepiapte
交叉反应：Human, Mouse, Rat, Pig, Horse, Rabbit,
细胞定位：细胞浆
墨蝶蛉还原酶抗体产物介绍：background: This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. [provided by RefSeq, Jul 2008] Function: Catalyzes the final one or two reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin. Subunit: Homodimer.墨蝶蛉还原酶抗体 Subcellular Location: Cytoplasm. Post-translational modifications: In vitro phosphorylation of Ser-213 by CaMK2 does not change kinetic parameters. DISEASE: Defects in SPR are the cause of dystonia DOPA-responsive due to sepiapterin reductase deficiency (DRDSPRD) [MIM:612716]. In the majority of cases, patients manifest progressive psychomotor retardation, dystonia and spasticity. Cognitive anomalies are also often present. The disease is due to severe dopamine and serotonin deficiencies in the central nervous system caused by a defect in BH4 synthesis.墨蝶蛉还原酶抗体 Dystonia is defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures. Similarity: Belongs to the sepiapterin reductase family. Gene ID: 6697 Database links: Entrez Gene: 6697 Human Omim: 182125 Human SwissProt: P35270 Human Unigene: 301540 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
墨蝶蛉还原酶抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学 信号转导 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid