棕榈酰蛋白水解酶2抗体
规格:1尘驳/1尘濒
英文名: PPT2
别名: Lysosomal thioesterase PPT2; Palmitoyl protein hydrolase 2; Palmitoyl protein thioesterase 2; PPT 2; PPT-2; Ppt2; PPT2_HUMAN; S thioesterase G14; S-thioesterase G14.
分子量: 31kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PPT2 (22
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位:细胞浆
棕榈酰蛋白水解酶2抗体产物介绍:background: PPT2 (palmitoyl-protein thioesterase 2), also known as G14, is a 302 amino acid glycosylated protein that localizes to the lysosome and belongs to the palmitoyl-protein thioesterase family. Expressed throughout the body with highest levels in skeletal muscle, PPT2 functions to remove thioester-linked fatty acyl groups from a variety of substrates, including S-palmitoyl-CoA, thereby playing an important role in lipid metabolism. PPT2 operates at an optimal pH of 7 and exhibits the highest activity for 棕榈酰蛋白水解酶2抗体the acyl groups on myristic and palmitic acids, with lower levels of activity toward other short- and long-chain acyl substrates. PPT2 exists as two isoforms, one of which is expressed at low levels and is catalytically inactive. Function: Removes thioester-linked fatty acyl groups from various substrates including S-palmitoyl-CoA. Has the highest S-thioesterase activity for the acyl groups palmitic and myristic acid followed by 棕榈酰蛋白水解酶2抗体other short- and long-chain acyl substrates. However, because of structural constraints, is unable to remove palmitate from peptides or proteins. Subcellular Location: Lysosome. Tissue Specificity: Broadly expressed, with highest levels in skeletal muscle. Similarity: Belongs to the palmitoyl-protein thioesterase family. Database links: UniProtKB/Swiss-Prot: Q9UMR5.4 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
棕榈酰蛋白水解酶2抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 神经生物学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid