多巴胺顿1受体相互作用蛋白抗体
规格：1尘驳/1尘濒
英文名： Calcyon
别名： CALCYON; Drd1ip; Caly; CALY_HUMAN; D1 dopamine receptor interacting protein; Drd1ip; Neuron specific vesicular protein calcyon; Neuron-specific vesicular protein calcyon; NSG3; RP11-122K13.5.
分子量： 23kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Calcyon
交叉反应：Human, Mouse, Rat, Dog, Rabbit,
细胞定位：细胞浆 细胞膜
多巴胺顿1受体相互作用蛋白抗体产物介绍：background: Calcyon is a single transmembrane protein that interacts with D1 dopamine receptors. Dopamine is a neurotransmitter that regulates synaptic transmission involved in learning and memory. D1 receptors, the most abundant dopamine receptor in the central nervous system, appear to modulate the activity of D2 dopamine receptors, mediate various behavioural responses, and regulate neuron growth and differentiation. Calcyon is present in neuronal cell bodies and processes of the cortex and 多巴胺顿1受体相互作用蛋白抗体hippocampus, and it is especially abundant in pyramidal neurons. Interaction of Calcyon with D1 receptors results in a release of intracellular calcium. Function: Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis. Subunit: nteracts with CLTA. Subcellular Location: Cytoplasmic vesicle membrane. Cell membrane. Tissue Specificity: Expressed in 多巴胺顿1受体相互作用蛋白抗体the pyramidal cells of the prefrontal cortex, in hippothalamus and in caudate nucleus. No expression in spleen. Up-regulated in the prefrontal cortex of schizophrenic patients with nearly twice the levels of non-schizophrenics. Post-translational modifications: Glycosylated. Similarity: Belongs to the NSG family. Database links: Entrez Gene: 50632 Human Entrez Gene: 68566 Mouse Entrez Gene: 192349 Rat Omim: 604647 Human SwissProt: Q9NYX4 Human SwissProt: Q9DCA7 Mouse SwissProt: P58821 Rat Unigene: 148680 Human Unigene: 44241 Mouse Unigene: 27756 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
多巴胺顿1受体相互作用蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 细胞膜受体 跨膜蛋白 细胞膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid