神经母细胞瘤源性分泌蛋白抗体
规格：1尘驳/1尘濒
英文名： C1orf76
别名： C1orf76; NDSP; FAM163A; Chromosome 1 open reading frame 76; F163A_HUMAN; Fam163a; hypothetical protein MGC16664; NDSP; Neuroblastoma derived secretory protein; Neuroblastoma-derived secretory protein;
分子量： 18kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NDSP (12
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位：细胞膜
神经母细胞瘤源性分泌蛋白抗体产物介绍：background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1神经母细胞瘤源性分泌蛋白抗体 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. 神经母细胞瘤源性分泌蛋白抗体The C1orf76 gene product has been provisionally designated C1orf76 pending further characterization. Subcellular Location: Membrane; Single-pass membrane protein (Potential). Tissue Specificity: Highly expressed in neuroblastoma compared to other tissues, suggesting that it may be used as a marker for metastasis in bone marrow. Similarity: Belongs to the FAM163 family. Database links: Entrez Gene: 148753 Human Entrez Gene: 329274 Mouse SwissProt: Q96GL9 Human SwissProt: Q8CAA5 Mouse Unigene: 729631 Human Unigene: 150857 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经母细胞瘤源性分泌蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid