3-羟氨苯甲酸双加氧酶抗体
规格：1尘驳/1尘濒
英文名： HAAO
别名： 3 HAO; 3 hydroxyanthranilate 3 4 dioxygenase; 3 hydroxyanthranilate dioxygenase; 3 hydroxyanthranilate oxygenase; 3 hydroxyanthranilic acid dioxygenase; 3-HAO; 3-hydroxyanthranilate 3; 3-hydroxyanthra
分子量： 33kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HAAO
交叉反应：Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep,
细胞定位：细胞浆
3-羟氨苯甲酸双加氧酶抗体产物介绍：background: The 3-HAO family of proteins consists of intramolecular dioxygenases that contain non-heme ferrous iron. HAAO (3-hydroxyanthranilate 3,4-dioxygenase), also known as HAO or 3-HAO, is a 286 amino acid monomeric cytoplasmic protein that belongs to the 3-HAO family. Utilizing Fe2+ ions as a cofactor, HAAO participates in the formation of quinolinic acid (QUIN), and excitotoxin, by catalyzing the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde. HAAO may3-羟氨苯甲酸双加氧酶抗体 play a role in disorders that are associated with varying levels of QUIN expression, and is widely expressed in peripheral organs, including kidney and liver. Existing as two alternatively spliced isoforms, the gene encoding HAAO maps to human chromosome 2p21 and mouse chromosome 17 E4. Function: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde,3-羟氨苯甲酸双加氧酶抗体 which spontaneously cyclizes to quinolinate. Subcellular Location: Cytoplasm. Similarity: Belongs to the 3-HAO family. Gene ID: 23498 Database links: Entrez Gene: 23498 Human Entrez Gene: 107766 Mouse Entrez Gene: 56823 Rat Omim: 604521 Human SwissProt: P46952 Human SwissProt: Q78JT3 Mouse SwissProt: P46953 Rat Unigene: 368805 Human Unigene: 30100 Mouse Unigene: 48675 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
3-羟氨苯甲酸双加氧酶抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 神经生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid