蛋白质精氨酸亚型2抗体
规格：1尘驳/1尘濒
英文名： PADI2
别名： PADI2 / PAD2; PAD 2; PAD2; PAD H19; PAD-H19; PADI 2; Padi2; PADI2 protein; PADI2_HUMAN; PDI 2; PDI2 antibody Peptidlyarginine deiminase type II; Peptidyl arginine deiminase II; Peptidyl arginine deimi
分子量： 76kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PADI2/PA
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：细胞浆
蛋白质精氨酸亚型2抗体产物介绍：background: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and 蛋白质精氨酸亚型2抗体macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008] Function: Catalyzes the deimination of arginine residues of proteins. Subcellular Location: 蛋白质精氨酸亚型2抗体Cytoplasm. Similarity: Belongs to the protein arginine deiminase family. Database links: Entrez Gene: 11240 Human Entrez Gene: 18600 Mouse Entrez Gene: 29511 Rat Omim: 607935 Human SwissProt: Q96DA7 Human SwissProt: Q9Y2J8 Human SwissProt: Q08642 Mouse SwissProt: Q75WD0 Mouse SwissProt: P20717 Rat Unigene: 33455 Human Unigene: 2296 Mouse Unigene: 469220 Mouse Unigene: 98523 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
蛋白质精氨酸亚型2抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学 信号转导 Alzheimer's
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid