β淀粉样蛋白前体蛋白结合蛋白2抗体
规格：1尘驳/1尘濒
英文名： APPBP2
别名： amyloid beta precursor protein (cytoplasmic tail) binding protein 2; Amyloid beta precursor protein-binding protein 2; Amyloid protein binding protein 2; Amyloid protein-binding protein 2; APBP2_HUMAN
分子量： 67kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human APPBP2
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Zebrafish,
细胞定位：细胞核 细胞浆
β淀粉样蛋白前体蛋白结合蛋白2抗体产物介绍：background: The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene. [provided by RefSeq, Jul 2008]. Function: β淀粉样蛋白前体蛋白结合蛋白2抗体May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface. Subunit: Binds APP. Subcellular Location: Nucleus. Cytoplasm Post-translational modifications: Rapidly degraded by the proteasome upon overexpression of a C-terminal fragment of APP. Similarity: Contains 8 TPR repeats. Database links: Entrez Gene: 10513 Humanβ淀粉样蛋白前体蛋白结合蛋白2抗体 Entrez Gene: 66884 Mouse Entrez Gene: 303396 Rat Entrez Gene: 417645 Chicken Omim: 605324 Human SwissProt: Q92624 Human SwissProt: Q9DAX9 Mouse SwissProt: A5HK05 Rat Unigene: 84084 Human Unigene: 271997 Mouse Unigene: 104856 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
β淀粉样蛋白前体蛋白结合蛋白2抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 神经生物学 Alzheimer's
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid