巨噬细胞炎症蛋白2（ GRＯβ）抗体
规格：1尘驳/1尘濒
英文名： CXCL2/GRO Beta
别名： C-X-C motif chemokine 2; Chemokine (C X C motif) ligand 2; Chemokine, CXC motif, ligand 2; CINC 2a; CINC2a; CINC3; CXC chemokine; CXCL 2; CXCL2; MIP2; MIP 2; MIP-2; Cytokine-induced neutrophil chemoat
分子量： 12kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MIP2
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞浆 分泌型蛋白
巨噬细胞炎症蛋白2（ GRＯβ）抗体产物介绍：background: GRO beta is a member of the CXC, or chemokine class. It contains the ELR domain immediately preceding the first cysteine residue near the amino terminus. Other chemokines in this group include IL8, GRO alpha/beta/gamma, mouse KC, ENA78, GCP2, PBP/CTAPIII/beta TG/NAP2. These chemokines act primarily on neutrophils as chemoattractants and activators, including neutrophil degradation with release of myloperoxidase and other enzymes. GRO beta was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. GRO beta is an approximately 8 kDa polypeptide of 巨噬细胞炎症蛋白2（ GRＯβ）抗体73 amino acids. The precursor form of GRO beta consists of 100 amino acids. To generate the mature GRO beta, the precursor cleaves its amino terminal 27 amino acids. GRO beta shows 60% amino acid homology to human GRO alpha and GRO gamma. Function: Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity. Subcellular Location: Secreted. Post-translational modifications: The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow 巨噬细胞炎症蛋白2（ GRＯβ）抗体stromal cells. Similarity: Belongs to the intercrine alpha (chemokine CxC) family. Gene ID: 2920 Database links: Entrez Gene: 2920 Human Entrez Gene: 20310 Mouse Entrez Gene: 114105 Rat SwissProt: P19875 Human SwissProt: P10889 Mouse SwissProt: P30348 Rat Unigene: 75765 Human Unigene: 10230 Rat Omim: 139110 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
巨噬细胞炎症蛋白2（ GRＯβ）抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid