鸟苷酸环化酶激活蛋白1抗体
规格：1尘驳/1尘濒
英文名： Guanylin
别名： GapI; GCAP-I; Guanylate cyclase activating protein 1; Guanylate cyclase activator 2A (guanylin 2 intestinal heat-stable); Guanylate cyclase activator 2A; Guanylate cyclase-activating protein 1; Guanyl
分子量： 10kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Guanylin
交叉反应：Human, Pig, Cow, Horse, Sheep,
细胞定位：分泌型蛋白
鸟苷酸环化酶激活蛋白1抗体产物介绍：background: The family of guanylin regulatory peptides, including guanylin and uroguanylin, are strongly expressed in intestinal mucosa and regulate intestinal fluid secretion during digestion. Guanylins are also involved in acid neutralization and the regulation of membrane-bound guanylate cyclase signaling molecules. Guanylin and uroguanylin are secreted primarily in the stomach, intestine, and colon. Guanylin is also detected in plasma. Guanylin is an endogenous activator of intestinal guanylate cyclase. It stimulates intestina鸟苷酸环化酶激活蛋白1抗体 guanylate cyclase through the same receptor binding region as the heat-stable enterotoxins. Gut enterochromaffin cells synthesize guanylin to be a prohormone of 115 amino acids which is then is processed to the molecular form of 94 amino acids. This 10kDa form is found circulating in the blood. Function: Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. Subcellular Location: Secreted. Tissue Specificity: Highly expressed in ileum and colon.鸟苷酸环化酶激活蛋白1抗体 Found in plasma. Similarity: Belongs to the guanylin family. Database links: Entrez Gene: 2980 Human Entrez Gene: 14915 Mouse Entrez Gene: 25656 Rat Omim: 139392 Human SwissProt: Q02747 Human SwissProt: P33680 Mouse SwissProt: P28902 Rat Unigene: 778 Human Unigene: 2614 Mouse Unigene: 11388 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
鸟苷酸环化酶激活蛋白1抗体产物应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 生长因子和** 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid