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低密度脂蛋白受体5样蛋白抗体

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产物名称: 低密度脂蛋白受体5样蛋白抗体
产物型号: LRP5L
产物展商: 单克隆抗体/多克隆抗体
产物文档: 无相关文档

简单介绍

低密度脂蛋白受体5样蛋白抗体应用于IHC、WB、 IF、IP、ELISA等科研实验,按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源,可将其分为天然抗体和**抗体。低密度脂蛋白受体5样蛋白抗体生产每个流程都执行严格的检测标准,保证蛋白抗原产物质量,质量稳定,实验效果明显。


低密度脂蛋白受体5样蛋白抗体  的详细介绍

低密度脂蛋白受体5样蛋白抗体

规格:1尘驳/1尘濒

英文名: LRP5L

别名: Low-density lipoprotein receptor-related protein 5-like protein; LRP-5-like; LRP5L; GP330; LRP5L_HUMAN.

分子量: 28kDa

储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型:笔辞濒测肠濒辞苍补濒

亚型:滨驳骋

纯化方法:affinity purified by Protein A

**原:KLH conjugated synthetic peptide derived from human LRP5L (1

交叉反应:Human, Mouse, Rat, Chicken, Sheep,

细胞定位:

低密度脂蛋白受体5样蛋白抗体产物介绍:background: Members of the LDL receptor gene family, including LDLR (low density lipo-protein receptor), LRPs (low density lipoprotein related proteins), Megalin (also designated GP330), VLDLR (very low density lipoprotein receptor) and ApoER2, are characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. Of the known family members, LRP5 is most closely related to LRP1. However, LRP5 has a unique organization of EGF低密度脂蛋白受体5样蛋白抗体 and LDLR repeats compared to other LDLR family members and likely represents a new category in this family. LRP is expressed in rat tibia, specifically in areas of the bone that are involved in remodeling. LRP5 is a Wnt coreceptor that binds to Axin and regulates the canonical Wnt signaling pathway. LRP5 affects bone mass accrual during growth. Mutations in LRP5 cause the autosomal recessive disorder osteoporosis-pseudoglioma syndrome (OPPG). LRP5L is a related protein that exists as two isoforms produced by alternative splicing. Similarity: Contains 5 LDL-receptor低密度脂蛋白受体5样蛋白抗体 class B repeats. Database links: UniProtKB/Swiss-Prot: A4QPB2.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

低密度脂蛋白受体5样蛋白抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域:细胞生物  发育生物学  细胞周期蛋白  转录调节因子  表观遗传学  细胞膜蛋白  

储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源: Rabbit

外观: Lyophilized or Liquid


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