搁丑辞家族骋罢笔酶2抗体
规格：1尘驳/1尘濒
英文名： RND2/Rho7
别名： ARHN; Rho 7; Rho family GTPase 2; Rho N; Rho related GTP-binding protein RhoN; Rho-related GTP-binding protein Rho7; Rho-related GTP-binding protein RhoN; Rho7; RhoN; Rnd 2; Rnd2; RND2_HUMAN.
分子量： 25kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human RND2 (1-
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞浆 细胞膜
搁丑辞家族骋罢笔酶2抗体产物介绍：background: The Ras p21 family of guanine nucleotide proteins has been widely studied in view of its apparent role in signal transduction pathways and high frequency of mutations in human malignancies. It is now clear, however, that the Ras proteins (H-, K- and N-Ras p21) are members of a much larger superfamily of related proteins. Six members of this family, Rap 1A, Rap 1B, Rap 2, R-Ras, Ral A and Ral B, exhibit approximately 50% amino acid homology to Ras. The six mammalian Rho proteins (Rho A, B, C, G, 7 and 8) are approximately 30% homologous to Ras and are expressed in a wide range of cell types. Both Ras p21 and Rho p21, as well as other members of the Ras 搁丑辞家族骋罢笔酶2抗体superfamily, contain a carboxy-terminal CAAX sequence (C, cysteine; A, aliphatic amino acid; X, any amino acid) which in the case of Ras has been shown to be essential for correct localization and function. Function: May be specifically involved in neuronal and hepatic functions. Is a C3 toxin-insensitive member of the Rho subfamily. Subunit: Interacts with the Rho-GAP domain of RACGAP1. Interacts with UBXD5. Subcellular搁丑辞家族骋罢笔酶2抗体 Location: Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Lipid-anchor; Cytoplasmic side (Potential). Note=Colocalizes with RACGAP1 in Golgi-derived proacrosomal vesicles and the acrosome. Tissue Specificity: Highly expressed in testis. Similarity: Belongs to the small GTPase superfamily. Rho family. Gene ID: 8153 Database links: Entrez Gene: 8153 Human Entrez Gene: 11858 Mouse Entrez Gene: 303553 Rat Omim: 601555 Human SwissProt: P52198 Human SwissProt: Q9QYM5 Mouse Unigene: 603111 Human Unigene: 378883 Mouse Unigene: 22162 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
搁丑辞家族骋罢笔酶2抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 信号转导 G蛋白偶联受体 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid