钙调神经磷酸酶调节蛋白1抗体
规格：1尘驳/1尘濒
英文名： Calcipressin 1/DSCR 1
别名： Adapt 78; Adapt78; Calcipressin 1; Calcipressin-1; Calcium and oxidant inducible mRNA; CSP 1; CSP1; Down syndrome candidate region 1; Down syndrome critical region gene 1; Down syndrome critical regio
分子量： 28kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Calcipre
交叉反应：Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, Sheep,
细胞定位：
钙调神经磷酸酶调节蛋白1抗体产物介绍：background: The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been钙调神经磷酸酶调节蛋白1抗体 found for this gene. [provided by RefSeq, Jul 2008]. Function: Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development. Subunit: Interacts with RAF1. Tissue Specificity: Highly expressed heart, brain and skeletal muscle. Also expressed in all other tissues. Similarity: Belongs to the RCAN family. 钙调神经磷酸酶调节蛋白1抗体Database links: Entrez Gene: 1827 Human Entrez Gene: 54720 Mouse Entrez Gene: 266766 Rat Omim: 602917 Human SwissProt: P53805 Human SwissProt: Q9JHG6 Mouse SwissProt: Q6IN33 Rat Unigene: 282326 Human Unigene: 265744 Mouse Unigene: 12942 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
钙调神经磷酸酶调节蛋白1抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid