神经***转化酶2抗体
规格:1尘驳/1尘濒
英文名: PCSK2/Proprotein Convertase 2
别名: KEX2 like endoprotease 2; KEX2-like endoprotease 2; NEC 2; NEC2; NEC2_HUMAN; Neuroendocrine convertase 2; PC2; PCSK2; Prohormone convertase 2; Proprotein convertase 2; Proprotein convertase subtilisin
分子量: 58kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Proprote
交叉反应:Human, Mouse, Rat, Chicken, Dog, Cow, Sheep,
细胞定位:细胞浆
神经***转化酶2抗体产物介绍:background: This gene encodes a member of the subtilisin-like proprotein convertase family. These enzymes process latent precursor proteins into their biologically active products. The encoded protein plays a critical role in hormone biosynthesis by processing a variety of prohormones including proinsulin, proopiomelanocortin and proluteinizing-hormone-releasing hormone. Single nucleotide polymorphisms in this gene may increase susceptibility to myocardial infarction and type 2 diabetes. This gene may also play a 神经***转化酶2抗体role in tumor development and progression. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]. Function: Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Subcellular Location: Cytoplasmic vesicle, secretory vesicle. Note=Localized in the secretion granules.神经***转化酶2抗体 Similarity: Belongs to the peptidase S8 family. Furin subfamily. Database links: Entrez Gene: 5126 Human Entrez Gene: 18549 Mouse Omim: 162151 Human SwissProt: P16519 Human SwissProt: P21661 Mouse Unigene: 315186 Human Unigene: 294493 Mouse Unigene: 447466 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经***转化酶2抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 神经生物学 信号转导 生长因子和**
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid