神经甘丙肽样肽骋础尝笔抗体
规格：1尘驳/1尘濒
英文名： GALP
别名： Alarin; Alarin splice variant; Galanin like peptide; Galanin like peptide precursor protein; GALP precursor protein; GALP_HUMAN.
分子量： 6kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GALP (25
交叉反应：贬耻尘补苍,
细胞定位：分泌型蛋白
神经甘丙肽样肽骋础尝笔抗体产物介绍：background: This gene encodes a member of the galanin family of neuropeptides. The encoded protein binds galanin receptors 1, 2 and 3 with the highest affinity for galanin receptor 3 and has been implicated in biological processes involving the central nervous system including hypothalamic regulation of metabolism and reproduction. A peptide encoded by a splice variant of this gene, termed alarin, may have vasoactive properties and serve as a marker for neuroblastic tumors.[provided by RefSeq, Mar 2009]. Function: This gene encodes a member of the galanin family of neuropeptides. The encoded protein binds galanin receptors 1, 2 and 3 with the highest 神经甘丙肽样肽骋础尝笔抗体affinity for galanin receptor 3 and has been implicated in biological processes involving the central nervous system including hypothalamic regulation of metabolism and reproduction. A peptide encoded by a splice variant of this gene, termed alarin, may have vasoactive properties and serve as a marker for neuroblastic tumors. Isoform 2 exhibits potent and dose-dependent vasoconstrictor and anti-edema activity in the cutaneous microvasculature, a physiologic effect which does not appear to be mediated via GALR1 or GALR2. Subcellular Location: Secreted. Tissue神经甘丙肽样肽骋础尝笔抗体 Specificity: Isoform 2 is found in ganglia of ganglioneuroma and ganglioneuroblastoma, as well as in differentiated tumor cells of neuroblastoma tissues. Not found in undifferentiated neuroblasts. Isoform 2 is found in the skin, in pericytes covering microvascular arterioles and venules on their abluminal surfaces. In larger vessels, isoform 2 is expressed in layers of smooth muscle cells. Isoform 2 is not detected in endothelial cells. Similarity: Belongs to the galanin family. Database links: Entrez Gene: 85569 Human Omim: 611178 Human SwissProt: Q9UBC7 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经甘丙肽样肽骋础尝笔抗体产物应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 心血管 细胞生物 发育生物学 神经生物学 生长因子和** G蛋白偶联受体 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid