黑素皮质素受体5抗体
规格：1尘驳/1尘濒
英文名： MC5 Receptor
别名： MC-2; MC2; MC5 R; MC5-R; MC5R; MC5R_HUMAN; Melanocortin 5 receptor; Melanocortin receptor 5.
分子量： 37kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MC5 Rece
交叉反应：Human, Mouse, Rabbit,
细胞定位：细胞膜
黑素皮质素受体5抗体产物介绍：background: The melanocortin family comprises the Alpha-, Beta- and Gamma- melanocyte stimulating hormones (MSH) and adrenocorticotrophin. The receptors for these hormones are seven-transmembrane G protein-coupled proteins that activate adenylyl cyclase. Five melanocortin receptors have been cloned and shown to exhibit different affinities and patterns of expression. MC1-R (MSH-R) is expressed in melanocytes and corticoadrenal tissue. MC2-R is the ACTH receptor and is expressed primarily in the adrenal cortex. MC3-R has been found in specific regions of the brain and is also expressed in placenta and gut. MC4-R is expressed primarily in brain, while黑素皮质素受体5抗体 MC5-R is expressed at low levels in most tissues. Function: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins. Subcellular Location: Cell membrane. Tissue Specificity: Expressed in the brain but not in the melanoma cells. Similarity: Belongs to the G-protein coupled receptor 1 family. Gene ID: 4161 Database links: Entrez Gene: 4161 Human Entrez Gene: 17203 Mouse Entrez Gene: 25726 Rat Omim:黑素皮质素受体5抗体 600042 Human SwissProt: P33032 Human SwissProt: P41149 Mouse SwissProt: P35345 Rat Unigene: 248145 Human Unigene: 8003 Mouse Unigene: 9673 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
黑素皮质素受体5抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学 信号转导 G蛋白偶联受体 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid