脑型肉碱棕榈酰转移酶1颁抗体
规格:1尘驳/1尘濒
英文名: Cpt1c
别名: CPT1-C; Carnitine acyltransferase like protein 1; Carnitine acyltransferase like protein1; Carnitine O palmitoyltransferase I, brain isoform; Carnitine palmitoyltransferase 1, brain; Carnitine palmito
分子量: 88kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Cpt1c (1
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位:细胞浆 细胞膜 线粒体
脑型肉碱棕榈酰转移酶1颁抗体产物介绍:background: The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA脑型肉碱棕榈酰转移酶1颁抗体 levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, 脑型肉碱棕榈酰转移酶1颁抗体Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine. Subcellular Location: Mitochondrion outer membrane; Multi-pass membrane protein Tissue Specificity: Expressed predominantly in brain and testis. Similarity: Belongs to the carnitine/choline acetyltransferase family. Database links: UniProtKB/Swiss-Prot: Q8TCG5.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
脑型肉碱棕榈酰转移酶1颁抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 心血管 细胞生物 神经生物学 信号转导 ***病 线粒体
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid