睾丸特异激酶底物蛋白抗体
规格：1尘驳/1尘濒
英文名： TSKS
别名： STK22 substrate 1; Stk22s1; Testis specific kinase substrate; Testis specific serine kinase substrate; TSKS; TSKS1; MGC134104; TSKS_HUMAN.
分子量： 65kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TSKS (12
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
细胞定位：细胞浆
睾丸特异激酶底物蛋白抗体产物介绍：background: TSKS is a 592 amino acid protein that is highly expressed in human testicular tissue. Low levels of TSKS are detectable in prostate, placenta, fetal liver, thymus, and mammary gland tissues. TSKS is found to be downregulated in cancerous testicular tissue from seminoma, teratocarcinoma, embryonal and Leydig cell tumors concurrently with high expression in neighboring premalignant carcinoma. TSKS protein contains an N-terminal signal peptide, but does not contain a transmembrane region. TSKS has many potential phosphorylation and glycosylation sites and is phosphorylated by soluble recombinant TSSK2 in vitro. It is thought that TSKS睾丸特异激酶底物蛋白抗体 likely plays a physiological role in spermatogenesis or spermiogenesis. Function: A novel putative serine/threonine kinase substrate gene (TSKS, for testis-specific kinase substrate) is likely the human homolog of the mouse testis-specific serine kinase substrate gene. TSKS exhibits high levels of expression exclusively in human testicular tissue. The expression of TSKS is downregulated in cancerous testicular tissue, in comparison to adjacent normal tissue. These observations suggest a role of TSKS in testicular physiology, most probably in the process of睾丸特异激酶底物蛋白抗体 spermatogenesis or spermiogenesis. Subcellular Location: Cytoplasmic Tissue Specificity: Highly expressed in testis. Expressed at low levels in prostate, female breast, placenta, ovary and thymus. Post-translational modifications: Phosphorylated on serine residue(s) by STK22A/TSSK1 and STK22B/TSSK2. Database links: UniProtKB/Swiss-Prot: Q9UJT2.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
睾丸特异激酶底物蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 发育生物学 神经生物学 信号转导 干细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid