囊泡相关膜蛋白8抗体
规格：1尘驳/1尘濒
英文名： VAMP8
别名： EDB; Endobrevin; VAMP 5; VAMP-5; VAMP 8; VAMP-8; VAMP5; VAMP8; VAMP8_HUMAN; Vesicle associated membrane protein 8; Vesicle-associated membrane protein 8.
分子量： 11kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human VAMP8 (3
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位：细胞膜
囊泡相关膜蛋白8抗体产物介绍：background: Syntaxins were originally thought to be docking proteins, but have more recently been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins bind to various proteins involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF (N-ethylmaleimide-sensitive factor), SNAPs (soluble NSF attachment proteins) and Synaptotagmin. Endobrevin, also designated VAMP-8 or ED, is a 100 amino acid single-pass type IV membrane protein that belongs to the synaptobrevin family. Similar in sequence to the synaptobrevins, endobrevin is abundantly expressed in kidney, moderately expressed in heart and spleen, and slightly expressed in brain, thymus and liver. Endobrevin interacts specifically with the SNAPs, most likely through an 囊泡相关膜蛋白8抗体endobrevin-containing SNARE complex. Function: Involved in the targeting and/or fusion of transport vesicles to their target membrane. Involved for dense-granule secretion in platelets. Plays a role in regulated enzyme secretion in pancreatic acinar cells. Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells. Involved in the homotypic fusion of early and late endosomes. Subunit: Found in a number of SNARE complexes with NAPA, SNAP23, SNAP25, STX1A, STX4, STX7, STX8 and VTI1B (By similarity). Interacts with STX8 (By similarity). Subcellular Location: Membrane; Single-pass type IV membrane protein. Tissue Specificity: Platelets. Similarity: Belongs to the 囊泡相关膜蛋白8抗体synaptobrevin family. Contains 1 v-SNARE coiled-coil homology domain. Database links: Entrez Gene: 8673 Human Entrez Gene: 22320 Mouse Entrez Gene: 83730 Rat Omim: 603177 Human SwissProt: Q9BV40 Human SwissProt: O70404 Mouse SwissProt: Q9WUF4 Rat Unigene: 714302 Human Unigene: 1838 Mouse Unigene: 82672 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
囊泡相关膜蛋白8抗体产物应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 细胞分化
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid