神经细胞囊泡循环蛋白1抗体
规格:1尘驳/1尘濒
英文名: Synaptogyrin 1
别名: SNG1_HUMAN;Synaptogyrin-1;Syngr1.
分子量: 26kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Synaptog
交叉反应:Human, Mouse, Rat,
细胞定位:细胞膜
神经细胞囊泡循环蛋白1抗体产物介绍:background: The synaptogyrin family of proteins are integral membrane proteins containing four transmembrane regions. Synaptogyrins are tyrosine-phosphorylated proteins with two neuronal isoforms (Synaptogyrin-1 and -3) and one ubiquitous isoform (Synaptogyrin-2). Synaptophysin and synaptogyrin represent the major constituents of synaptic vesicles. Synaptogyrin-1 is associated with presynaptic vesicles in neuronal cells. Synaptogyrin-2, also known as cellugyrin, has a tyrosine phosphorylated C-terminal cytoplasmic tail and is involved in the regulation of membrane traffic in non-neuronal cells. Synaptogyrin-3 is expressed mainly in brain and placenta. 神经细胞囊泡循环蛋白1抗体Synaptogyrin-4 is a 234 amino acid protein encoded by the SYNGR4 gene. Function: Involved in the regulation of short-term and long-term synaptic plasticity. Subcellular Location: Membrane; Multi-pass membrane protein. Melanosome. Cell junction, synapse. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Similarity: Belongs to the synaptogyrin family. Contains 1 MARVEL domain. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 囊泡循环蛋白,神经细胞囊泡循环蛋白1抗体Synaptogyrin又称p29,是均一分布于神经系统的突触囊泡蛋白,在神经元及神经***细胞高度表达,它是酪氨酸激酶的一个重要的囊泡相关底物。synaptogyrin为多基因家族编码,异构体的cDNA序列同源性为32%~46%。人的囊泡循环蛋白 cDNA有一阅读框架,编码234个氨基酸,分子量约25,683Da,有四个跨膜域,N端与C端朝向囊泡的胞质面,无糖基化位点,蛋白分子胞浆尾的氨基酸序列与Syp有74%的同源性。
神经细胞囊泡循环蛋白1抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 神经生物学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid