生长抑素抗体
规格：1尘驳/1尘濒
英文名： Somatostatin 28
别名： GRIH; Growth hormone release inhibiting factor; SMS_HUMAN; SMST; SST; Somatostatin 14; Somatostatin14; Somatostatin-14; somatostatin SS14; Somatostatin 28; Somatostatin28; Somatostatin-28; somatostati
分子量： 13kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Somatost
交叉反应：Human, Mouse, Rat, Chicken, Pig, Cow, Sheep,
生长抑素抗体细胞定位：分泌型蛋白
产物介绍：background: The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. [provided by RefSeq,生长抑素抗体 Jul 2008]. Function: Somatostatin inhibits the release of somatotropin. Subcellular Location: Secreted. Similarity: Belongs to the somatostatin family. Gene ID: 6750 Database links: Entrez Gene: 396279 Chicken Entrez Gene: 280932 Cow Entrez Gene: 6750 Human Entrez Gene: 20604 Mouse Entrez Gene: 24797 Rat Omim: 182450 Human SwissProt: P33094 Chicken SwissProt: P26917 Cow SwissProt: P61278 Human SwissProt: P60041 Mouse SwissProt: P60042 Rat Unigene: 12409 Human Unigene: 34418 Rat Important Note: This product as supplied is intended for research 生长抑素抗体use only, not for use in human, therapeutic or diagnostic applications. 生长抑素是胰岛D细胞的一种多肽**，主要用于胰岛细胞的功能性分类和消化道粘膜中***细胞及肿瘤的研究。 生长抑素在体内分布广泛。在神经系统中，广泛存在于**和外周神经系统，在脑内以下丘脑正中隆起的浓度为*高。在新皮层，边缘系统下杏仁核，海马等部位也广泛存在，以皮层含量*高。在脊髓后根和三叉神经神经节内的**神经元中，亦含生长抑素的**反应性物质。生长抑素广泛存在于胃肠道粘膜的“D”细胞，以胃窦和胃体*高，在肠内越往下含量越低。“D”细胞有长的胞浆突起，在幽门腺区止于G细胞和“嗜铬细胞”，在泌酸腺区止于壁细胞和其他上皮细胞。生长抑素通过旁分泌机制由突起释放到G细胞和壁细胞膜上，抑制胃泌素和HCI分泌，在胰腺内，生长抑素由胰岛“D”细胞分泌，通过血液循环对胰岛及消化道起作用，作为旁分泌调节胰岛功能。 生长抑素的生理作用为：抑制垂体生长**、促甲状腺**、促肾上腺皮质**和催乳类的释放，也抑制各种胃肠**的释放，抑制胃泌素、促胰液素、胆囊收缩素、胃动素、胰多肽、胰高血糖素、肠高血糖素等的释放。同时也抑制胃酸、胃蛋白酶、胰蛋白酶及唾液淀粉酶的分泌。
生长抑素抗体产物应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 生长因子和**
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid