细胞粘附分子伴侣蛋白2抗体
规格:1尘驳/1尘濒
英文名: Sidekick 2
别名: SDK2; SDK 2; SDK-2; SDK2; Sidekick 2; Sidekick homolog 2 (chicken); sidekick-2; Sidekick2; FLJ10832; KIAA1514; SDK2_HUMAN.
分子量: 237kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Sidekick
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep,
细胞定位:细胞膜
细胞粘附分子伴侣蛋白2抗体产物介绍:background: Sidekick-2 (SDK2), also known as KIAA1514, is a 2,172 amino acid single-pass type I membrane protein containing thirteen fibronectin type-III domains and six Ig-like C2-type (immunoglobulin-like) domains. Acting as a cell adhesion protein, Sidekick-2 guides axonal terminals to synapses in developing neurons. Sidekick-2 may require the interaction with MAGI scaffolding proteins for proper localization and function. Existing as four alternatively spliced isoforms, the gene encoding Sidekick-2 maps to human chromosome 17q25.1. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Neurofibromatosis, 细胞粘附分子伴侣蛋白2抗体a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth have been linked to chromosome 17. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17. Function: Sidekick 2 is a cell adhesion protein that guides axonal terminals to specific synapses in developing neurons. Subcellular Location: Membrane; Single-pass type I membrane protein (Potential). Similarity: Contains 13 fibronectin type-III domains. Contains 6 Ig-like C2-type (immunoglobulin-like) 细胞粘附分子伴侣蛋白2抗体domains. Database links: UniProtKB/Swiss-Prot: Q58EX2.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞粘附分子伴侣蛋白2抗体产物应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 神经生物学 细胞粘附分子 细胞膜蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid