神经元膜糖蛋白锚定蛋白2抗体
规格：1尘驳/1尘濒
英文名： MDGA2
别名： MAM domain-containing glycosylphosphatidylinositol anchor protein 2; MAM domain-containing protein 1; MAMDC1; Mdga2; MDGA2_HUMAN; UNQ8188/PRO23197; c14_5286.
分子量： 102kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MDGA2
交叉反应：Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep,
细胞定位：细胞膜
神经元膜糖蛋白锚定蛋白2抗体产物介绍：background: MDGA2 is a cell membrane protein which contains six Ig-like (immunoglobulin-like) domains and one MAM domain. Analyses of the full-length coding region of MDGA1 and MDGA2 indicate that they encode proteins that comprise a novel subgroup of the Ig superfamily and have a unique structural organization consisting of six immunoglobulin (Ig)-like domains followed by a single MAM domain. Biochemical characterization demonstrates that MDGA1 and MDGA2 proteins are highly glycosylated, and that 神经元膜糖蛋白锚定蛋白2抗体MDGA1 is tethered to the cell membrane by a GPI anchor. The MDGAs are differentially expressed by subpopulations of neurons in both the central and peripheral nervous systems, including neurons of the basilar pons, inferior olive, cerebellum, cerebral cortex, olfactory bulb, spinal cord, and dorsal root and trigeminal ganglia. The similarity of MDGAs to other Ig-containing molecules and their temporal-spatial patterns of expression within restricted neuronal populations, for example migrating pontine neurons and D1 spinal interneurons, 神经元膜糖蛋白锚定蛋白2抗体suggest a role for these novel proteins in regulating neuronal migration, as well as other aspects of neural development, including axon guidance. Function: May involved in cell-cell interactions. Subcellular Location: Cell membrane. Similarity: Contains 6 Ig-like (immunoglobulin-like) domains. Contains 1 MAM domain. Database links: UniProtKB/Swiss-Prot: Q7Z553.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经元膜糖蛋白锚定蛋白2抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 信号转导 细胞凋亡 细胞粘附分子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid