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血管粘附蛋白1抗体

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产物名称: 血管粘附蛋白1抗体
产物型号:
产物展商: 单克隆抗体/多克隆抗体
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简单介绍

血管粘附蛋白1抗体应用于IHC、WB、 IF、IP、ELISA等科研实验,按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源,可将其分为天然抗体和**抗体。血管粘附蛋白1抗体生产每个流程都执行严格的检测标准,保证蛋白抗原产物质量,质量稳定,实验效果明显。


血管粘附蛋白1抗体  的详细介绍

血管粘附蛋白1抗体

规格:1尘驳/1尘濒

英文名: VAP1

别名: vascular adhesion protein 1; Amine oxidase, copper containing 3 (vascular adhesion protein 1); AOC3; Copper amine oxidase; HPAO; Membrane copper amine oxidase; Semicarbazide sensitive amine oxidase; S

分子量: 84kDa

储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型:笔辞濒测肠濒辞苍补濒

亚型:滨驳骋

纯化方法:affinity purified by Protein A

**原:KLH conjugated synthetic peptide derived from human VAP1

交叉反应:Human, Mouse, Rat,

细胞定位:

血管粘附蛋白1抗体产物介绍:background: This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants. [血管粘附蛋白1抗体provided by RefSeq, Apr 2013] Function: Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has a monoamine oxidase activity. May play a role in adipogenesis. Subcellular Location: Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has a monoamine oxidase activity. May play a role in 血管粘附蛋白1抗体adipogenesis. Tissue Specificity: Strongly expressed on the high endothelial venules of peripheral lymph nodes and on hepatic endothelia. Also highly expressed in appendix, lung and small intestine. Expressed also in adipose tissue, in bone marrow, colon, heart, kidney, ovary, pancreas, placenta, prostate, skeletal muscle, spleen and testis. Post-translational modifications: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue. N- and O-glycosylated. Similarity: Belongs to the copper/topaquinone oxidase family. Database links:   UniProtKB/Swiss-Prot: Q16853.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

血管粘附蛋白1抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域:心血管  神经生物学  信号转导  细胞粘附分子  血管内皮细胞  细胞骨架  Alzheimer's  

储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源: Rabbit

外观: Lyophilized or Liquid


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